causing mental discomfort

a feeling of mild anxiety about possible developments

An abnormal condition of a part, organ, or system of an organism resulting from various causes, such as infection, inflammation, environmental factors, or genetic defect, and characterized by an identifiable group of signs, symptoms, or both, an impairment of health or a condition of abnormal functioning, verb_ To infect with a disease, obsolete To cause unease; to annoy, irritate, transitive verb_ obsolete To deprive of ease; to disquiet; to trouble; to distress, To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased

Requiring care and labor; difficult or irksome, Marked by or requiring great care and diligence, Full of pain; causing uneasiness or distress, either physical or mental; afflictive; disquieting; distressing

Penalty; punishment suffered or denounced; suffering or evil inflicted as a punishment for a crime, or annexed to the commission of a crime, Uneasiness of mind; mental distress; disquietude; anxiety; solicitude; grief; sorrow, transitive verb_ To put to bodily uneasiness or anguish; to afflict with uneasy sensations of any degree of intensity; to torment; to torture, To render uneasy in mind; to disquiet; to distress; to grieve, obsolete To inflict suffering upon as a penalty; to punish